TriNutra is sharing new findings on its ThymoQuin black seed oil ingredient at SupplySide Global 2026, highlighting the connection between gut bacteria and the body's stress response. The research includes multiple studies showing that a daily dosage of 500 mg of ThymoQuin is linked to reductions in cortisol, improved sleep quality, and beneficial changes in gut microbiome composition.
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Key results indicate cortisol reductions of 23% to 44%, a 29% improvement in the DHEA:cortisol ratio, and a 31% increase in sleep quality. Notably, an in vitro study exhibited a significant increase in the growth of Streptococcus thermophilus and a 94% inhibition of Klebsiella pneumoniae. However, higher concentrations showed broad antimicrobial effects, suggesting a narrow effective range for optimal benefits that may not align with typical human gut conditions.
Morris Zelkha, CEO of TriNutra, emphasized the importance of these findings in understanding the Gut-Stress-Axis and expressed the company’s commitment to ongoing research to further explore ThymoQuin's effects on stress resilience and microbiome health.
While the research provides promising insights, it is essential for manufacturers to approach the findings cautiously. Current data stems from a single in vitro model, and additional peer-reviewed studies are necessary to validate the results and understand their implications for clinical applications.